Below is a summary of your responses from the mayzent.com questionnaire. Keep it handy, and share it with your doctor so you can have a conversation about how your symptoms might be changing over time.
I was first diagnosed with multiple sclerosis (MS) ago.
I still experiencing relapses.
I feel like I bouncing back in between relapses.
I had a recent MRI.
Overall, I like something is different or that my symptoms are changing.
I'm experiencing or feeling like the following have gotten worse compared to 6 to 12 months ago:
These activities are more challenging now compared to 6 to 12 months ago:
You may want to ask the following questions at your next appointment:
Tell your doctor about all the medicines you take, including prescription medicines, over-the-counter medicines, vitamins, and herbal supplements. Also tell your doctor about any other MS medications you've taken in the past.
Notes or questions for your doctor:
What is MAYZENT® (siponimod) tablets?
MAYZENT is a prescription medicine that is used to treat relapsing forms of multiple sclerosis, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
It is not known if MAYZENT is safe and effective in children.
IMPORTANT SAFETY INFORMATION
Do not take MAYZENT if you:
Please see additional Important Safety Information on pages 2-3 and full Prescribing Information, including Medication Guide, at mayzent.com.
IMPORTANT SAFETY INFORMATION (cont)
MAYZENT® may cause serious side effects, including:
Slow heart rate (bradycardia or bradyarrhythmia) when you start taking MAYZENT. MAYZENT can cause your heart rate to slow down, especially after you take your first dose. You should have a test to check the electrical activity of your heart called an electrocardiogram (ECG) before you take your first dose of MAYZENT.
During the initial updosing period (4 days for the 1-mg daily dose or 5 days for the 2-mg daily dose), if you miss 1 or more doses of MAYZENT, you need to restart the updosing. Call your health care provider if you miss a dose of MAYZENT.
Infections. MAYZENT can increase your risk of serious infections that can be life-threatening and cause death. MAYZENT lowers the number of white blood cells (lymphocytes) in your blood. This will usually go back to normal within 3 to 4 weeks of stopping treatment. Your health care provider should review a recent blood test of your white blood cells before you start taking MAYZENT. Call your health care provider right away if you have any of these symptoms of an infection during treatment with MAYZENT and for 3 to 4 weeks after your last dose of MAYZENT:
A problem with your vision called macular edema. Macular edema can cause some of the same vision symptoms as a multiple sclerosis (MS) attack (optic neuritis). You may not notice any symptoms with macular edema. If macular edema happens, it usually starts in the first 1 to 4 months after you start taking MAYZENT. Your health care provider should test your vision before you start taking MAYZENT and any time you notice vision changes during treatment with MAYZENT. Your risk of macular edema is higher if you have diabetes or have had an inflammation of your eye called uveitis.
Call your health care provider right away if you have any of the following: blurriness or shadows in the center of your vision, a blind spot in the center of your vision, sensitivity to light, or unusually colored (tinted) vision.
Before taking MAYZENT, tell your health care provider about all of your medical conditions, including if you:
Please see additional Important Safety Information on pages 1 and 3 and full Prescribing Information, including Medication Guide, at mayzent.com.
IMPORTANT SAFETY INFORMATION (cont)
Tell your health care provider about all the medicines you take, including prescription medicines, over-the-counter medicines, vitamins, and herbal supplements. Especially tell your health care provider if you take medicines to control your heart rhythm (anti-arrhythmics), or blood pressure (antihypertensives), or heart beat (such as calcium channel blockers or beta-blockers); take medicines that affect your immune system, such as beta-interferon or glatiramer acetate, or any of these medicines that you took in the past.
Tell your health care provider if you have recently received a live vaccine. You should avoid receiving live vaccines during treatment with MAYZENT®. MAYZENT should be stopped 1 week before and for 4 weeks after receiving a live vaccine. If you receive a live vaccine, you may get the infection the vaccine was meant to prevent. Vaccines may not work as well when given during treatment with MAYZENT.
MAYZENT may cause possible side effects, including:
The most common side effects of MAYZENT include: headache, high blood pressure (hypertension), and abnormal liver tests.
These are not all of the possible side effects of MAYZENT. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see additional Important Safety Information on pages 1-2 and full Prescribing Information, including Medication Guide, at mayzent.com.
MAYZENT and the MAYZENT logo are registered trademarks of Novartis AG.
Novartis Pharmaceuticals Corporation
East Hanover, New Jersey 07936-1080